IRTX is an important new compound that appears to be a very potent vanilloid receptor antagonist. IRTX binds to the VR1 receptor with high affinity (Kd = 4.3 nM) but does not induce RTX- or capsaicin-like effects in Xenopus laevis oocytes expressing VR1. Mol. Pharm. 59: 9-15 (2001).
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary Statements
P261: Avoid breathing <dust/fumes/gas/mist/vapours/spray>.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear <protective gloves/protective clothing/eye protection/face protection>.
P312: Call a <POISON CENTER/doctor/...> if you feel unwell.: hazard.P261: Avoid breathing <dust/fumes/gas/mist/vapours/spray>.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear <protective gloves/protective clothing/eye protection/face protection>.
P312: Call a <POISON CENTER/doctor/...> if you feel unwell.
